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Best Pizza in Wilmington

Your Neighborhood Spot For Fresh Pizza Always
Homemade Dough. Real Ingredients. Every Day.

Homemade Dough. Real Ingredients. Every Day.

At Greg’s Pizza Route 38, great pizza starts from scratch. We make our dough and signature sauces fresh every single day, in-house on Main Street in Wilmington. Every pizza is built with real ingredients, bold flavor, and care in every step.
Pizza Made the Right Way

Pizza Made the Right Way

From classic cheese to our Hometown Favorite with sweet sauce, every pizza is freshly prepared and baked hot for the perfect slice every time.
Fresh Pizza Made Daily With Bold Flavor

Fresh Pizza Made Daily With Bold Flavor

At Greg’s Pizza Route 38, our top-selling pizzas are made fresh daily with homemade dough, house-made sauce, and quality ingredients. Customer favorites include Hometown Favorite with sweet sauce, Meat Lovers, BBQ Chicken, Greek Pizza, Buffalo Chicken, and Veggie Lovers. Every pizza is baked hot, made to order, and crafted for bold flavor that keeps Wilmington coming back for more.
Fresh Pizza Catering For Every Occasion

Fresh Pizza Catering For Every Occasion

Make your next event unforgettable with Greg’s Pizza Route 38 catering. From classic cheese and specialty pizzas to crowd-favorite slices made with fresh homemade dough and house-made sauce, we bring hot, fresh, and flavorful pizza straight to your gathering. Perfect for parties, office lunches, game nights, and celebrations of any size.
Specialty Pizzas, Full of Flavor

Specialty Pizzas, Full of Flavor

Explore bold favorites like BBQ Chicken, Meat Lovers, Veggie, Greek, Buffalo Chicken, and creative specialty pies like Tikka Masala and Greg’s Special.
Reserve Your Table At Greg’s Pizza Route 38

Reserve Your Table At Greg’s Pizza Route 38

Enjoy fresh, handcrafted pizza made daily with homemade dough and house-made sauce in a relaxed, welcoming setting. Whether it’s a family dinner, a casual night out, or a small gathering, reserve your table at Greg’s Pizza Route 38 and enjoy your favorite pizzas hot from the oven, served fresh in the heart of Wilmington.

What our guests are saying

First time trying it and I loved my calzone it was delicious. My fiance got the barbecue chicken wings with fries and that was delicious and then we got powdered sugar puff things and they were so so so so good. I will definitely be buying from Greg's again ¡! Definitely try it out, you will not be disappointed!!

Erica

Erica

Awesome great service and food is really good quality.Normal prices won't be heavy on pocket. Nice clean and cool place to start your mid day or evening.Sub,Salad,Pizza or seafood is awesome. Try them won't be disappointed that all I can promise. Take out or delivery either dine in,these guys are rocking stars. 10 stars they deserved, if I can gave them. Good luck 👍

Syed Sherazi

Syed Sherazi

Stopped here on my way home. I had a big roast beef sandwich which was packed with tender beef, the perfect amount of sauce, and onion. Prices are good and the food hits the spot. I definitely recommend trying Greg’s.

 Apex Imagery

Apex Imagery

This place has the best calzones! We got steak and cheese along with buffalo chicken. The top has a delicious crispy cheese top. No other plans does their calzones like this. It's really stuffed and the crust is delicious. Their prices are good too. I would highly recommend this place to all I know and meet. Now I want to try other things on their menu. It's quit big. Food is always hot and delicious. Please come visit this place. You won't be disappointed.

Tracy D

Tracy D

Wilmington’s Local Pizza Spot

Greg’s Pizza Route 38 has been serving handcrafted pizza for years with homemade dough, house-made sauce, and recipes made for true pizza lovers.

Catering

Let us cater your next event. Click below to get started.

Reservations

We are happy to accept reservations through our website, to get started, click the link below.

Frequently Asked Questions

Our location

Map showing the location of Greg's Pizza Route 38 on 101 Main St in Wilmington

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